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Original research (Published On: 10-Nov-2022 )

Phytochemicals quantification, tlc and antimicrobial assessment of leaves and fruit extracts of Lasimorpha senegalensis (schott) araceae

Bunu J. Samuel, Miediegha Oyeintonbara, Owaba Azibanasamesa, Ozor Martins and Chukwuemerie Ogechukwu

J. Chem. Res. Adv., 03 (02):14-20

Bunu J. Samuel : Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmacy, Niger Delta University, Wilberforce Island, Nigeria

Miediegha Oyeintonbara : Faculty of Pharmacy, Niger Delta University, Wilberforce Island, Nigeria

Owaba Azibanasamesa : Faculty of Pharmacy, Niger Delta University, Wilberforce Island, Nigeria

Ozor Martins : Faculty of Pharmacy, Niger Delta University, Wilberforce Island, Nigeria

Chukwuemerie Ogechukwu : Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Nigeria

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Article History: Received on: 02-Aug-22, Accepted on: 04-Nov-22, Published on: 10-Nov-22

Corresponding Author: Bunu J. Samuel

Email: Pharmsamuelbunu@gmail.com

Citation: Samuel BJ, Oyeintonbara M, Azibanasamesa ODC, Martins OO and Ogechukwu CL (2022). Phytochemicals quantification, tlc and antimicrobial assessment of leaves and fruit extracts of Lasimorpha senegalensis (schott) araceae. J. Chem. Res. Adv., 03 (02 ):14-20


Abstract

Aim: This study was aimed to conduct phytochemical screening and evaluate the antimicrobial properties of Lasimorpha senegalensis.

Method and Materials: The leaves and fruit parts of Lasimorpha senegalensis (Schott) Araceae were collected at Korokorosei community in Bayelsa State, air-dried, pulverized, and extracted using dichloromethane, ethanol, methanol and water. Flavonoids, saponins, tannins, ketones, and cardiac glycosides were all found to be present. Preliminary thin layer chromatographic screening of the extracts was also done, as well as the antibacterial evaluation of the different fractions using the agar diffusion technique.

Results: The phytochemical screening for tannins, cardiac glycoside, ketones, and flavonoids was positive.  Inhibition zones for the aqueous fraction at 62.5, 125, 250, and 500 mg/ml for E. coli were 32, 22, 18, and 11 mm respectively, while 8, 9, 10, and 14 mm for Pseudomonas aeruginosa. For the methanolic fraction, at the above concentrations, 10, 11, 14 and 14 nm were observed as zones of inhibition on Escherichia coli, 14, 19, 15, and 20 nm for Pseudomonas aeruginosa and 19, 20, 20, and 20 nm for Staphylococcus aureus, respectively. Furthermore, in the dichloromethane fraction, 13, 20, 19, and 15 nm were observed as zones of inhibition on Escherichia coli, 8, 10, 15 and 15 nm for Pseudomonas aeruginosa and 20, 15, 20, and 18 nm for Staphylococcus aureus, respectively.

Conclusion: It was concluded that the leaf portion of the plants can be used in the treatment of infections caused by E. col, Pseudomonas aeruginosa, and Staphylococcus aureus. With the high amounts of flavonoids observed, it can be employed as an antioxidant and a cardioprotective.


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