Abstract

Aim: The study was aimed to investigate the phytochemical profile, antioxidant, and antimicrobial efficacy of crude extracts from Persea americana seed.

Method and Materials: Phytochemical profile of various crude extracts obtained using different solvents in their order of polarity was determined using standard methods. All the crude extracts of Persea americana seed were subjected to 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay. Seven pathogenic microbes were used for antimicrobial activity of seed extracts using agar gel diffusion technique.

Results: The phytochemical analysis result of Persea americana seed extracts confirmed the presence of tannins, steroid, terpenoids, flavonoids, glycosides, and alkaloid. All seed extracts demonstrated very good antioxidant potentials against DPPH radical scavenging. The methanol seed extract showed a significant antimicrobial activity against all the tested micro-organism. The inhibitory potential of the seed extracts increases with increasing concentration, and polarity of solvent. The results exhibited good selective sensitivity against various tested pathogens.

Conclusion: It was concluded that the screened seed extracts of Persea americana is a good source of natural strong antioxidant, and antimicrobial agents validating the traditional use of the seed in folk medicine.

Statistics