Manuela Cecille G. Vicencio
J. Chem. Res. Adv., 02 (01):01-05
Manuela Cecille G. Vicencio : College of Science, University of Eastern Philippines, Philippines
Aim: This study was aimed to determine the antibacterial efficacy of the ethyl alcohol and ethyl acetate leaf extracts of Paederia foetida that can inhibit the growth of microorganisms causing disease and to identify the presence of alkaloid, flavonoids, saponins and tannins as secondary metabolites.
Method and Materials: Determination of antimicrobial effect was done using the paper-disc method and and Kirby-Bauer antibacterial sensitivity test against Staphyloccocous aureus and Eschirichia coli. Result showed that leaf extracts of P. foetida showed antibacterial activity against bacteria S. aureus and E. coli. Mean zone of inhbition was numerically higher in plates extract obtained using ethyl alcohol (22.70 - 21mm), compared to extract obtained using ethyl acetate as solvent.
Results: Results of phytochemical screening showed that extract of the leaves of P. foetida contains alkaloids, saponins and tannins but not with the flavonoids.
Conclusion: It was concluded that leaf
of Paederia foetida could be a potent antimicrobial agent for use in the field